Glutathione Skin Brightener™ with Ceramosides®
NOW® Solutions Glutathione Skin Brightener™ with Ceramosides® features glutathione, which is a free radical neutralizer powerhouse essential for maintaining youthful skin and Ceramosides®, a low-dose, fast-acting wheat extract, abundant in phytoceramides.*
Oral Ceramides & Digalactosyl Diglycerides (DGDG) for Skin Hydration & Age-Related Appearance Study
Monocentric, double-blind, placebo-controlled, randomized study; 60 healthy females (aged 30-60 years) with dry skin and signs of skin aging; 30 mg/day for 60 days.
Results: Significant improvements in skin hydration, elasticity, and smoothness, along with reductions in skin roughness, wrinkledness, and transepidermal water loss (TEWL).* Benefits were noticeable as early as 15 days and continued throughout the study, suggesting that WPLC (wheat polar lipids complex) is a promising supplement for enhancing skin health and combating aging-related skin concerns.*
Wheat Lipid Supplementation for Dry & Aging Skin Study
Randomized, double-blind, placebo-controlled, parallel study; 72 healthy women (aged 30-60 years); 30 mg/day for 8 weeks.
Results: Significant improvement in skin moisturization, elasticity and smoothness as early as two weeks after the beginning of supplementation with persistent increase throughout the eight weeks of the study.* Significant reduction of water loss, roughness and wrinkle depth as early as two weeks, this reduction is maintains throughout the eight weeks of the study.* Same significant results on all these parameters were observed in the subgroup of postmenopausal women.*
Glutathione & Skin Effects Study
Randomized, double-blind, placebo-controlled study; 60 healthy South Asian volunteers (aged 19-22 years); 250 mg twice daily for 4 weeks (twice the suggested dose in this product).
Results: Significant statistical difference in reduction of melanin index vs. baseline at end of the study for all tested area (face, sun-exposed forearm, sun protected forearm).* There was a greater reduction in melanin index in the glutathione group as compared to placebo on all sun-exposed areas.* There was a significantly smaller number of UV spots developed in subjects receiving glutathione vs. placebo.*
Glutathione & Skin Effects Study
Open-label, single-arm pilot study; 30 healthy South Asian volunteers (Fitzpatrick skin types IV or V, aged 22-42 years); 500 mg/day lozenge to melt in mouth before swallowing for 8 weeks (twice the suggested dose in this product).
Results: Significant statistical difference in reduction of melanin index vs. baseline at end of the study for both sun-exposed, and sun-protected skin.*
References:
- Bizot, Valérie, et al. "Improving skin hydration and age-related symptoms by oral administration of wheat glucosylceramides and digalactosyl diglycerides: a human clinical study." Cosmetics 4.4 (2017): 37.
- Kern C, Dudonné S, Garcia C. Dietary supplementation with a wheat polar lipid complex improves skin conditions in women with dry skin and mild-to-moderate skin aging. J Cosmet Dermatol. 2024;23(4):1320-30.
- Arjinpathana, Nutthavuth, and Pravit Asawanonda. "Glutathione as an oral whitening agent: a randomized, double-blind, placebo-controlled study." Journal of dermatological treatment 23.2 (2012): 97-102.
- Handog, Evangeline B., Maria Suzanne L. Datuin, and Ivan A. Singzon. "An open‐label, single‐arm trial of the safety and efficacy of a novel preparation of glutathione as a skin‐lightening agent in F ilipino women." International journal of dermatology 55.2 (2016): 153-157.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
