* Supplements include vitamins, botanicals and minerals used to supplement one’s diet. The U.S. Food and Drug Administration (FDA) regulates both finished dietary supplement products and dietary ingredients under a different set of regulations than those covering other types of foods.
† The FDA defines an adverse event as any undesirable experience associated with the use of a product. Serious means that one or more of the following outcomes were documented in the report: death, hospitalization, life-threatening, disability, congenital anomaly and/or other serious outcome. Documenting one or more of these outcomes in a report does not necessarily mean that the suspect product(s) named in the report was the cause of these outcomes.7
Pharmacist-driven consumer database: http://www.naturalproductsinfo.org/index.php?submenu=Health_Info&src=gendocs&ref=Lookup&category=Lookup
NIH Office of Dietary Supplements Fact Sheets: http://ods.od.nih.gov/factsheets/list-all/
2 Council for Responsible Nutrition http://www.crnusa.org/consumersurvey
3 Kantor, Elizabeth D. etc. al. Trends in Prescription Drug Use Among Adults in the United States From 1999-2012 JAMA. 2015;314(17):1818-1830.
7 U.S. Food and Drug Administration https://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Surveillance/AdverseDrugEffects/ucm070461.htmz
10Natural Products Insider March 31, 2016