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Your Bromelain tablets are labeled as having a potency of 2000 gdu/gram, yet I see that the Bromelain in Item 2996, Plant Enzyme Complex, is labeled as FCC (PU) units. What is the difference and is there a conversion between the two?
Bromelain can be standardized on Milk Clot Units (MCU/mg), Casein Digestion Units (CDU/mg), Bromelain Tyrosine Units (BTU/ gram), Rorer units, and more.
One FCC Papain Unit (PU), for example, is defined in this assay as that quantity of enzyme that liberates the equivalent of 1 µg (microgram) of tyrosine per hour under the conditions of the assay. This procedure is also used to determine the proteolytic activity of ficin and bromelain. The assay is based on a 60-min proteolytic hydrolysis of a casein substrate at pH 6.0 and 40° C. Soluble casein is then measured spectrophotometrically at 280nm.
Different activity-measuring methods can use different protein substrates as well as methods. Since enzymes are specific to peptide bonds and whicht terminal end of an amino acid it will cleave, there typically will not be a conversion between measures unless both measures are performed. This is why conversion among different enzyme measures can be so difficult.
In the case of the single ingredient formula, Bromelain at 2000 GDU/g would be equal to a 30,000,000 FCC PU/g potency.
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