
Omega-3 Fats Found to Help Colorectal Health
By Greg Arnold, DC, CSCS, May 27, 2008, abstracted from A 22-year Prospective Study of Fish, n-3 Fatty Acid Intake, and Colorectal Cancer Risk in Men in the May 2008 issue of the Cancer Epidemiology Biomarkers and Prevention
Colorectal cancer is the second leading cause of death from cancer (behind lung cancer) in the United States, claiming more than 55,000 Americans each year. It poses a risk for an estimated 1 in 4 Americans (80 to 90 million) because of age or other factors and, contrary to what most people believe, both men and women are equally affected1.
Fortunately, calcium2, conjugated linoleic acid3, vitamin B64, green tea5, fiber6, olive oil7 and apples8 have been shown to benefit colon health. Now a new study8 has found more evidence that omega-3 fats, previously found to help with colorectal health9, continues to benefit colorectal health.
In the study, over 22,000 doctors from the Physicians Health Study11 completed a questionnaire on fish intake12. The researchers identified cases of colorectal cancer and found that those consuming fish at least five times per week had a 37% reduced risk of colorectal cancer compared to those consuming fish less than once per week. Those consuming fish 2-5 times per week had an 18% reduced risk and those consuming fish 1-2 times per week had a 12% reduced risk of colorectal cancer.
Regarding omega-3 fatty acid intake, those in the highest 25% of intake had a 21% reduced risk of colorectal cancer (although the amounts of omega-3 fatty acid intake were not given by the researchers). Nevertheless, the researchers concluded that intake of fish and long-chain omega-3 fatty acids from fish may decrease the risk for colorectal cancer.
Greg Arnold is a Chiropractic Physician practicing in Danville, CA. You can contact Dr. Arnold directly by emailing him at mailto:PitchingDoc@msn.com or visiting his web site at www.CompleteChiropracticHealthcare.com
Reference:
1 Colorectal Cancer Fact Sheet posted on the Foundation for Digestive Health and Nutrition Website www.fdhn.org/html/education/colorectal/facts.html
2 Meunier, P. J. (1999). "Calcium, vitamin D and vitamin K in the prevention of fractures due to osteoporosis." Osteoporos Int 9 Suppl 2: S48-52
3 Larsson SC. High-fat dairy food and conjugated linoleic acid intakes in relation to colorectal cancer incidence in the Swedish Mammography Cohort. Am J Clin Nutr 2005 82: 894-900
4 Theodoratou E. Dietary Vitamin B6 Intake and the Risk of Colorectal Cancer. Cancer Epidemiol Biomarkers Prev 2008 17: 171-182 doi: 10.1158/1055-9965.EPI-07-0621
5 Yong G. Prospective Cohort Study of Green Tea Consumption and Colorectal Cancer Risk in Women. Cancer Epidemiol Biomarkers Prev 2007 16: 1219-1223 doi: 10.1158/1055-9965.EPI-07-0097
6 Jacobs ET. Fiber, sex, and colorectal adenoma: results of a pooled analysis. Am. J. Clinical Nutrition, Feb 2006; 83: 343 349
7 Gill, C. I., A. Boyd, et al. (2005). "Potential anti-cancer effects of virgin olive oil phenols on colorectal carcinogenesis models in vitro." Int J Cancer 117(1): 1-7
8 Waldecker M. Histone-deacetylase inhibition and butyrate formation: Fecal slurry incubations with apple pectin and apple juice extracts. Nutrition 2008; 24(4): 366-374
9 Hall MN. A 22-year Prospective Study of Fish, n-3 Fatty Acid Intake, and Colorectal Cancer Risk in Men. Cancer Epidemiol Biomarkers Prev 2008 17: 1136-1143 doi: 10.1158/1055-9965.EPI-07-2803
10 Kuriki K. Risk of Colorectal Cancer Is Linked to Erythrocyte Compositions of Fatty Acids as Biomarkers for Dietary Intakes of Fish, Fat, and Fatty Acids. Cancer Epidemiol Biomarkers Prev 2006 15: 1791-1798
11 Hall MN, Campos H, Li H, et al. Blood levels of long-chain polyunsaturated fatty acids, aspirin, and the risk of colorectal cancer. Cancer Epidemiol Biomarkers Prev 2007;16:31421












